iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer

iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer

Pancreatic cancer is one of the leading causes of cancer-related death, with 5-year survival of 8.5%. The lack of significant progress in improving therapy reflects our inability to overcome the desmoplastic stromal barrier in pancreatic ductal adenocarcinoma (PDAC) as well as a paucity of new appro...

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Bibliographic Details
Main Authors:	Lo, Justin H., Hao, Liangliang, Muzumdar, Mandar, Raghavan, Srivatsan, Kwon, Ester, Pulver, Emilia M, Hsu, Felicia, Aguirre, Andrew J., Wolpin, Brian M., Fuchs, Charles S., Hahn, William C., Jacks, Tyler E, Bhatia, Sangeeta N
Other Authors:	Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format:	Article
Language:	English
Published:	American Association for Cancer Research (AACR) 2020
Online Access:	https://hdl.handle.net/1721.1/128731

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