Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma

Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma

The prognosis for pancreatic ductal adenocarcinoma (PDAC) remains poor despite decades of effort. The abundant extracellular matrix (ECM) in PDAC comprises a major fraction of the tumor mass and plays various roles in promoting resistance to therapies. However, nonselective depletion of ECM has led...

Full description

Bibliographic Details
Main Authors: Tian, Chenxi, Öhlund, Daniel, Rickelt, Steffen, Lidström, Tommy, Huang, Ying, Hao, Liangliang, Zhao, Renee T, Franklin, Oskar, Bhatia, Sangeeta N, Tuveson, David A., Hynes, Richard O
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: American Association for Cancer Research (AACR) 2020
Online Access:https://hdl.handle.net/1721.1/128828

Similar Items

Similar Items