The Protein’s Role in Substrate Positioning and Reactivity for Biosynthetic Enzyme Complexes: The Case of SyrB2/SyrB1
Biosynthetic enzyme complexes selectively catalyze challenging chemical transformations, including alkane functionalization (e.g., halogenation of threonine, Thr, by the non-heme iron halogenase SyrB2). However, the role of complex formation in enabling reactivity and guiding selectivity is poorly u...
Main Authors: | Mehmood, Rimsha, Qi, Helena Wen, Steeves, Adam H., Kulik, Heather Janine |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2020
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Online Access: | https://hdl.handle.net/1721.1/128837 |
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