Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exogenous factors, numerous genes that affect the differentiation...

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Bibliographic Details
Main Authors:	Sharon, Nadav, Vanderhooft, Jordan, Straubhaar, Juerg, Mueller, Jonas Weylin, Chawla, Raghav, Zhou, Quan, Engquist, Elise N., Trapnell, Cole, Gifford, David K, Melton, Douglas A.
Other Authors:	Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format:	Article
Language:	English
Published:	Elsevier BV 2020
Online Access:	https://hdl.handle.net/1721.1/128920

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