Antibody complementarity determining region design using high-capacity machine learning
Motivation: The precise targeting of antibodies and other protein therapeutics is required for their proper function and the elimination of deleterious off-target effects. Often the molecular structure of a therapeutic target is unknown and randomized methods are used to design antibodies without a...
Main Authors: | Liu, Ge, Zeng, Haoyang, Mueller, Jonas Weylin, Carter, Brandon M., Wang, Ziheng, Schilz, Jonas, Horny, Geraldine, Birnbaum, Michael E, Ewert, Stefan, Gifford, David K |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | English |
Published: |
Oxford University Press (OUP)
2021
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Online Access: | https://hdl.handle.net/1721.1/129332 |
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