A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets
The pancreatic islets of Langerhans regulate glucose homeostasis. The loss of insulin-producing β cells within islets results in diabetes, and islet transplantation from cadaveric donors can cure the disease. In vitro production of whole islets, not just β cells, will benefit from a better understan...
Main Author: | Gifford, David K |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
|
Online Access: | https://hdl.handle.net/1721.1/129520 |
Similar Items
-
Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis
by: Mostafa Bakhti, et al.
Published: (2022-08-01) -
Inducible Mosaic Cell Labeling Provides Insights Into Pancreatic Islet Morphogenesis
by: Julia Freudenblum, et al.
Published: (2020-09-01) -
Chromosomal coordination and differential structure of asynchronous replicating regions
by: Britny Blumenfeld, et al.
Published: (2021-02-01) -
Differentiation of pancreatic endocrine islets in buffalo fetus
by: DIVYA GUPTA, et al.
Published: (2020-09-01) -
Two orthogonal differentiation gradients locally coordinate fruit morphogenesis
by: Andrea Gómez-Felipe, et al.
Published: (2024-04-01)