Target site specificity and in vivo complexity of the mammalian arginylome

Target site specificity and in vivo complexity of the mammalian arginylome

Protein arginylation mediated by arginyltransferase ATE1 is a key regulatory process essential for mammalian embryogenesis, cell migration, and protein regulation. Despite decades of studies, very little is known about the specificity of ATE1-mediated target site recognition. Here, we used in vitro...

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Bibliographic Details
Main Authors: Wang, Junling, Pejaver, Vikas Rao, Dann, Geoffrey P., Wolf, Maxim Y., Kellis, Manolis, Huang, Yun, Garcia, Benjamin A., Radivojac, Predrag, Kashina, Anna
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/129727

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