30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review
Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However,...
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| Format: | Article |
| Language: | English |
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Springer International Publishing
2021
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| Online Access: | https://hdl.handle.net/1721.1/129774 |
| _version_ | 1811071168413696000 |
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| author | Bardhan, Neelkanth Manoj |
| author_facet | Bardhan, Neelkanth Manoj |
| author_sort | Bardhan, Neelkanth Manoj |
| collection | MIT |
| description | Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However, for bio-applications, CANOMATs need to be surface-functionalized, to render them passive, non-toxic, and water-soluble. Here, we review the current state-of-the-art in the methods of functionalization of CANOMATs. In contrast to other Reviews, we present an objective analysis of the various approaches reported in the literature, using metrics such as the agent of functionalization, number of steps, and time required, the need for special instruments, effect on properties, scalability, reproducibility, and applications. Our Review offers a way for researchers to make a rational selection of the process of functionalization to best suit their desired application. This opens up new opportunities for developing targeted functionalization strategies, based on the need to excel at the above metrics. |
| first_indexed | 2024-09-23T08:47:05Z |
| format | Article |
| id | mit-1721.1/129774 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T08:47:05Z |
| publishDate | 2021 |
| publisher | Springer International Publishing |
| record_format | dspace |
| spelling | mit-1721.1/1297742021-02-17T03:32:19Z 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review Bardhan, Neelkanth Manoj Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However, for bio-applications, CANOMATs need to be surface-functionalized, to render them passive, non-toxic, and water-soluble. Here, we review the current state-of-the-art in the methods of functionalization of CANOMATs. In contrast to other Reviews, we present an objective analysis of the various approaches reported in the literature, using metrics such as the agent of functionalization, number of steps, and time required, the need for special instruments, effect on properties, scalability, reproducibility, and applications. Our Review offers a way for researchers to make a rational selection of the process of functionalization to best suit their desired application. This opens up new opportunities for developing targeted functionalization strategies, based on the need to excel at the above metrics. National Cancer Institute (U.S.) (Grant P30-CA14051) National Cancer Institute (U.S.) (for Cancer Nanotechnology Excellence Grant 5-U54-CA151884-03) United States. Army Research Office (Collaborative Biotechnologies (ICB) Grant #017251-022) 2021-02-16T19:46:26Z 2021-02-16T19:46:26Z 2016-12-19 2016-07 2021-02-07T04:55:10Z Article http://purl.org/eprint/type/JournalArticle 0884-2914 0884-1616 https://hdl.handle.net/1721.1/129774 Bardhan, Neelkanth M. “30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review.” Early Career Scholars in Journal of materials research, 32, 1 (December 2016) © 2016 The Author en https://doi.org/10.1557/jmr.2016.449 Journal of materials research Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Materials Research Society application/pdf Springer International Publishing Springer International Publishing |
| spellingShingle | Bardhan, Neelkanth Manoj 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_full | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_fullStr | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_full_unstemmed | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_short | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_sort | 30 years of advances in functionalization of carbon nanomaterials for biomedical applications a practical review |
| url | https://hdl.handle.net/1721.1/129774 |
| work_keys_str_mv | AT bardhanneelkanthmanoj 30yearsofadvancesinfunctionalizationofcarbonnanomaterialsforbiomedicalapplicationsapracticalreview |