Balance of interstitial flow magnitude and vascular endothelial growth factor concentration modulates three-dimensional microvascular network formation

Hemodynamic and biochemical factors play important roles in critical steps of angiogenesis. In particular, interstitial flow has attracted attention as an important hemodynamic factor controlling the angiogenic process. Here, we applied a wide range of interstitial flow magnitudes to an in vitro thr...

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Bibliographic Details
Main Authors: Abe, Yoshinori, Watanabe, Masafumi, Chung, Seok, Kamm, Roger Dale, Tanishita, Kazuo, Sudo, Ryo
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: AIP Publishing 2021
Online Access:https://hdl.handle.net/1721.1/129989