Enhancing phage therapy through synthetic biology and genome engineering
The antimicrobial and therapeutic efficacy of bacteriophages is currently limited, mostly due to rapid emergence of phage-resistance and the inability of most phage isolates to bind and infect a broad range of clinical strains. Here, we discuss how phage therapy can be improved through recent advanc...
Main Authors: | Lenneman, Bryan R, Fernbach, Jonas, Loessner, Martin J, Lu, Timothy K, Kilcher, Samuel |
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Other Authors: | Massachusetts Institute of Technology. Research Laboratory of Electronics |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/130337 |
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