The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2
The ongoing SARS-CoV-2 pandemic has highlighted the importance of the rapid development of vaccines and antivirals. However, the potential for the emergence of antibiotic resistances due to the increased use of antibacterial cleaning products and therapeutics presents an additional, underreported th...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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Elsevier BV
2021
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| Online Access: | https://hdl.handle.net/1721.1/130354 |
| _version_ | 1811094443398266880 |
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| author | Mahoney, Andrew R. Safaee, Mohammad Moein Wuest, William M. Furst, Ariel L. |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Mahoney, Andrew R. Safaee, Mohammad Moein Wuest, William M. Furst, Ariel L. |
| author_sort | Mahoney, Andrew R. |
| collection | MIT |
| description | The ongoing SARS-CoV-2 pandemic has highlighted the importance of the rapid development of vaccines and antivirals. However, the potential for the emergence of antibiotic resistances due to the increased use of antibacterial cleaning products and therapeutics presents an additional, underreported threat. Most antibacterial cleaners contain simple quaternary ammonium compounds (QACs), however these compounds are steadily becoming less effective as antibacterial agents. QACs are extensively used in SARS-CoV-2 related sanitization in clinical and household settings. Similarly, due to the danger of secondary infections, antibiotic therapeutics are increasingly used as a component of COVID-19 treatment regimens, even in the absence of a bacterial infection diagnosis. The increased use of antibacterial agents as cleaners and therapeutics is anticipated to lead to novel resistances in the coming years. |
| first_indexed | 2024-09-23T16:00:09Z |
| format | Article |
| id | mit-1721.1/130354 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T16:00:09Z |
| publishDate | 2021 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1303542022-10-02T05:40:11Z The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 Mahoney, Andrew R. Safaee, Mohammad Moein Wuest, William M. Furst, Ariel L. Massachusetts Institute of Technology. Department of Chemical Engineering The ongoing SARS-CoV-2 pandemic has highlighted the importance of the rapid development of vaccines and antivirals. However, the potential for the emergence of antibiotic resistances due to the increased use of antibacterial cleaning products and therapeutics presents an additional, underreported threat. Most antibacterial cleaners contain simple quaternary ammonium compounds (QACs), however these compounds are steadily becoming less effective as antibacterial agents. QACs are extensively used in SARS-CoV-2 related sanitization in clinical and household settings. Similarly, due to the danger of secondary infections, antibiotic therapeutics are increasingly used as a component of COVID-19 treatment regimens, even in the absence of a bacterial infection diagnosis. The increased use of antibacterial agents as cleaners and therapeutics is anticipated to lead to novel resistances in the coming years. 2021-04-02T19:27:59Z 2021-04-02T19:27:59Z 2021-03 2021-04-01T15:50:10Z Article http://purl.org/eprint/type/JournalArticle 2589-0042 https://hdl.handle.net/1721.1/130354 Mahoney, Andrew R. et al. "The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2." iScience 24, 4 (April 2021): 102304 © 2021 The Authors en http://dx.doi.org/10.1016/j.isci.2021.102304 iScience Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV Elsevier |
| spellingShingle | Mahoney, Andrew R. Safaee, Mohammad Moein Wuest, William M. Furst, Ariel L. The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title | The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title_full | The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title_fullStr | The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title_full_unstemmed | The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title_short | The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 |
| title_sort | silent pandemic emergent antibiotic resistances following the global response to sars cov 2 |
| url | https://hdl.handle.net/1721.1/130354 |
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