Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain

Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain

Particular brain regions and cell populations exhibit increased susceptibility to aging-related stresses. Here, we describe the age-specific and brain-region-specific accumulation of ribosome-associated 3′ UTR RNAs that lack the 5′ UTR and open reading frame. Our study reveals that this phenomenon i...

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Bibliographic Details
Main Authors: Sudmant, Peter, Lee, Hyeseung, Dominguez, Daniel, Heiman, Myriam, Burge, Christopher B.
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/130541

Internet

https://hdl.handle.net/1721.1/130541

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