Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2

Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune system in mediating these clinical outcomes has not been determined. We used multiparameter flow cytometry and systems serology to comprehen...

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Detalles Bibliográficos
Autores principales: Yu, Krystle K.Q., Fischinger, Stephanie, Smith, Malisa T., Atyeo, Caroline, Cizmeci, Deniz, Wolf, Caitlin R., Layton, Erik D., Logue, Jennifer K., Aguilar, Melissa S., Shuey, Kiel, Loos, Carolin, Yu, Jingyou, Franko, Nicholas, Choi, Robert Y., Wald, Anna, Barouch, Dan, Koelle, David M., Lauffenburger, Douglas, Chu, Helen Y., Alter, Galit, Seshadri, Chetan
Otros Autores: Ragon Institute of MGH, MIT and Harvard
Formato: Artículo
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Acceso en línea:https://hdl.handle.net/1721.1/130583