Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants

Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants

The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome effects on vaccine and treatment efficacy, but no current point-of-care (POC) testing modality allows their specific identific...

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Bibliographic Details
Main Authors: de Puig, Helena, Lee, Rose A., Najjar, Devora, Tan, Xiao, Soekensen, Luis R., Angenent-Mari, Nicolaas M., Donghia, Nina M., Weckman, Nicole E., Ory, Audrey, Ng, Carlos F., Nguyen, Peter Q., Mao, Angelo S., Ferrante, Thomas C., Lansberry, Geoffrey, Sallum, Hani, Niemi, James, Collins, James J.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: American Association for the Advancement of Science 2021
Online Access:https://hdl.handle.net/1721.1/131169

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