Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals present with isolated upper respiratory symptoms, suggesting potential to constrain viral pathology to the nasopharynx. Which cells SARS-CoV-2 primarily targets and how infection influences the respiratory epitheli...

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Bibliographic Details
Main Authors: Ziegler, Carly, Miao, Vincent N., Owings, Anna H., Navia, Andrew W., Tang, Ying, Bromley, Joshua D., Lotfy, Peter, Sloan, Meredith, Laird, Hannah, Williams, Haley B., George, Micayla, Drake, Riley S., Christian, Taylor, Parker, Adam, Sindel, Campbell B., Burger, Molly W., Pride, Yilianys, Hasan, Mohammad, Abraham, George E., Senitko, Michal, Robinson, Tanya O., Shalek, Alexander K, Glover, Sarah C., Horwitz, Bruce H., Ordovas-Montanes, Jose
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/131202

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