Rapid assessment of T-cell receptor specificity of the immune repertoire

Rapid assessment of T-cell receptor specificity of the immune repertoire

Accurate assessment of T-cell-receptor (TCR)–antigen specificity across the whole immune repertoire lies at the heart of improved cancer immunotherapy, but predictive models capable of high-throughput assessment of TCR–peptide pairs are lacking. Recent advances in deep sequencing and crystallography...

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Bibliographic Details
Main Authors: Lin, Xingcheng, George, Jason T., Schafer, Nicholas P., Ng Chau, Kevin, Birnbaum, Michael E, Clementi, Cecilia, Onuchic, José N., Levine, Herbert
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/131255

Internet

https://hdl.handle.net/1721.1/131255

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