In situ measurement of localization error in particle tracking microrheology

Abstract A method is presented to estimate the static error 𝜖 in a multiple particle tracking microrheology experiment. This in situ estimate of 𝜖 is measured under the same conditions of the material under test, and without any additional experiments. The correction of the mean-squar...

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Bibliographic Details
Main Authors: Josephson, Lilian L, Swan, James W, Furst, Eric M
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Springer Berlin Heidelberg 2021
Online Access:https://hdl.handle.net/1721.1/131424
Description
Summary:Abstract A method is presented to estimate the static error 𝜖 in a multiple particle tracking microrheology experiment. This in situ estimate of 𝜖 is measured under the same conditions of the material under test, and without any additional experiments. The correction of the mean-squared displacement by the in situ method is potentially more reliable than methods that rely on characterizing 𝜖 in a separate gel sample. With the true mean-squared displacements accessible at short lag times, experimental artifacts introduced by static error can be distinguished from true rheological properties, even in highly viscous (>10,000 mPa⋅s) samples.