MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review
Abstract Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechani...
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| Format: | Article |
| Language: | English |
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Springer International Publishing
2021
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| Online Access: | https://hdl.handle.net/1721.1/132033 |
| _version_ | 1811096410736558080 |
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| author | Bardhan, Neelkanth M |
| author2 | Massachusetts Institute of Technology. Department of Materials Science and Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Materials Science and Engineering Bardhan, Neelkanth M |
| author_sort | Bardhan, Neelkanth M |
| collection | MIT |
| description | Abstract
Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However, for bio-applications, CANOMATs need to be surface-functionalized, to render them passive, non-toxic, and water-soluble. Here, we review the current state-of-the-art in the methods of functionalization of CANOMATs. In contrast to other Reviews, we present an objective analysis of the various approaches reported in the literature, using metrics such as the agent of functionalization, number of steps, and time required, the need for special instruments, effect on properties, scalability, reproducibility, and applications. Our Review offers a way for researchers to make a rational selection of the process of functionalization to best suit their desired application. This opens up new opportunities for developing targeted functionalization strategies, based on the need to excel at the above metrics. |
| first_indexed | 2024-09-23T16:43:18Z |
| format | Article |
| id | mit-1721.1/132033 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T16:43:18Z |
| publishDate | 2021 |
| publisher | Springer International Publishing |
| record_format | dspace |
| spelling | mit-1721.1/1320332023-01-10T19:07:11Z MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review Bardhan, Neelkanth M Massachusetts Institute of Technology. Department of Materials Science and Engineering Massachusetts Institute of Technology. Department of Biological Engineering Koch Institute for Integrative Cancer Research at MIT Abstract Carbon-based nanomaterials (CANOMATs), including fullerenes, carbon nanotubes, graphene, and their derivatives, are widely considered to be the next-generation materials for a broad range of biomedical applications, owing to their unique opto-electronic, chemical, and mechanical properties. However, for bio-applications, CANOMATs need to be surface-functionalized, to render them passive, non-toxic, and water-soluble. Here, we review the current state-of-the-art in the methods of functionalization of CANOMATs. In contrast to other Reviews, we present an objective analysis of the various approaches reported in the literature, using metrics such as the agent of functionalization, number of steps, and time required, the need for special instruments, effect on properties, scalability, reproducibility, and applications. Our Review offers a way for researchers to make a rational selection of the process of functionalization to best suit their desired application. This opens up new opportunities for developing targeted functionalization strategies, based on the need to excel at the above metrics. 2021-09-20T17:41:34Z 2021-09-20T17:41:34Z 2016-12-19 2021-02-11T16:42:56Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/132033 PUBLISHER_CC en https://doi.org/10.1557/jmr.2016.449 Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Materials Research Society application/pdf Springer International Publishing Springer International Publishing |
| spellingShingle | Bardhan, Neelkanth M MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title | MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_full | MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_fullStr | MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_full_unstemmed | MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_short | MIGHT BE A DUPLICATE: 30 years of advances in functionalization of carbon nanomaterials for biomedical applications: a practical review |
| title_sort | might be a duplicate 30 years of advances in functionalization of carbon nanomaterials for biomedical applications a practical review |
| url | https://hdl.handle.net/1721.1/132033 |
| work_keys_str_mv | AT bardhanneelkanthm mightbeaduplicate30yearsofadvancesinfunctionalizationofcarbonnanomaterialsforbiomedicalapplicationsapracticalreview |