Synthesis of the EFG Framework of Tamulamides A and B
© 2019 American Chemical Society. Synthesis of the fused polycyclic ether motif comprising the EFG rings of the marine ladder polyethers tamulamides A and B has been achieved via two different etherification strategies. Ultimately, a reductive etherification approach proved most successful due to to...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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American Chemical Society (ACS)
2021
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| Online Access: | https://hdl.handle.net/1721.1/132391 |
| _version_ | 1826206787943006208 |
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| author | Kelley, Elizabeth H Jamison, Timothy F |
| author_facet | Kelley, Elizabeth H Jamison, Timothy F |
| author_sort | Kelley, Elizabeth H |
| collection | MIT |
| description | © 2019 American Chemical Society. Synthesis of the fused polycyclic ether motif comprising the EFG rings of the marine ladder polyethers tamulamides A and B has been achieved via two different etherification strategies. Ultimately, a reductive etherification approach proved most successful due to tolerance of the G ring substitution and provided the EFG 6,7,6 ring system in 58% yield. |
| first_indexed | 2024-09-23T13:38:33Z |
| format | Article |
| id | mit-1721.1/132391 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:38:33Z |
| publishDate | 2021 |
| publisher | American Chemical Society (ACS) |
| record_format | dspace |
| spelling | mit-1721.1/1323912021-09-21T03:27:56Z Synthesis of the EFG Framework of Tamulamides A and B Kelley, Elizabeth H Jamison, Timothy F © 2019 American Chemical Society. Synthesis of the fused polycyclic ether motif comprising the EFG rings of the marine ladder polyethers tamulamides A and B has been achieved via two different etherification strategies. Ultimately, a reductive etherification approach proved most successful due to tolerance of the G ring substitution and provided the EFG 6,7,6 ring system in 58% yield. 2021-09-20T18:22:10Z 2021-09-20T18:22:10Z 2020-10-19T14:45:52Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/132391 en 10.1021/ACS.ORGLETT.9B03015 Organic Letters Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Chemical Society (ACS) PMC |
| spellingShingle | Kelley, Elizabeth H Jamison, Timothy F Synthesis of the EFG Framework of Tamulamides A and B |
| title | Synthesis of the EFG Framework of Tamulamides A and B |
| title_full | Synthesis of the EFG Framework of Tamulamides A and B |
| title_fullStr | Synthesis of the EFG Framework of Tamulamides A and B |
| title_full_unstemmed | Synthesis of the EFG Framework of Tamulamides A and B |
| title_short | Synthesis of the EFG Framework of Tamulamides A and B |
| title_sort | synthesis of the efg framework of tamulamides a and b |
| url | https://hdl.handle.net/1721.1/132391 |
| work_keys_str_mv | AT kelleyelizabethh synthesisoftheefgframeworkoftamulamidesaandb AT jamisontimothyf synthesisoftheefgframeworkoftamulamidesaandb |