Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis
Copyright © 2020 American Chemical Society. C3-substituted 1H-indazoles are useful and important substructures in many pharmaceuticals. Methods for direct C3-functionalization of indazoles are relatively rare, compared to reactions developed for the more nucleophilic N1 and N2 positions. Herein, we...
Main Authors: | Ye, Yuxuan, Kevlishvili, Illia, Feng, Sheng, Liu, Peng, Buchwald, Stephen Leffler |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2022
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Online Access: | https://hdl.handle.net/1721.1/132536.2 |
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