In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

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© 2019 Elsevier Inc. Sangaré et al. use a CRISPR screen to determine the in vivo fitness of Toxoplasma genes. They identify a secreted protein, TgWIP, which determines dendritic cell motility and transmigration in the infected host. In mice, TgWIP determines T. gondii dissemination from the site of...

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Bibliographic Details
Main Authors:	Sangaré, Lamba Omar, Ólafsson, Einar B, Wang, Yifan, Yang, Ninghan, Julien, Lindsay, Camejo, Ana, Pesavento, Patricia, Sidik, Saima M, Lourido, Sebastian, Barragan, Antonio, Saeij, Jeroen PJ
Format:	Article
Language:	English
Published:	Elsevier BV 2021
Online Access:	https://hdl.handle.net/1721.1/132590

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