Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping of viral antigen-specific and unconventional T cell...

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Bibliographic Details
Main Authors: Youngs, Jonathan, Provine, Nicholas M., Lim, Nicholas, Sharpe, Hannah R., Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D., Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J., Duncan, David A., McNaughton, Anna L., Miao, Vincent N., Leaver, Susannah, Wyncoll, Duncan L. A., Ball, Jonathan, Hopkins, Philip, Skelly, Donal T., Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alexander K, Thompson, Craig P., Xue, Luzheng, Macallan, Derek C., Goulder, Philip, Klenerman, Paul, Bicanic, Tihana
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021
Online Access:https://hdl.handle.net/1721.1/132638

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