Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping of viral antigen-specific and unconventional T cell...

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Váldodahkkit: Youngs, Jonathan, Provine, Nicholas M., Lim, Nicholas, Sharpe, Hannah R., Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D., Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J., Duncan, David A., McNaughton, Anna L., Miao, Vincent N., Leaver, Susannah, Wyncoll, Duncan L. A., Ball, Jonathan, Hopkins, Philip, Skelly, Donal T., Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alexander K, Thompson, Craig P., Xue, Luzheng, Macallan, Derek C., Goulder, Philip, Klenerman, Paul, Bicanic, Tihana
Eará dahkkit: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2021
Liŋkkat:https://hdl.handle.net/1721.1/132638