Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping of viral antigen-specific and unconventional T cell...

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Manylion Llyfryddiaeth
Prif Awduron: Youngs, Jonathan, Provine, Nicholas M., Lim, Nicholas, Sharpe, Hannah R., Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D., Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J., Duncan, David A., McNaughton, Anna L., Miao, Vincent N., Leaver, Susannah, Wyncoll, Duncan L. A., Ball, Jonathan, Hopkins, Philip, Skelly, Donal T., Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alexander K, Thompson, Craig P., Xue, Luzheng, Macallan, Derek C., Goulder, Philip, Klenerman, Paul, Bicanic, Tihana
Awduron Eraill: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2021
Mynediad Ar-lein:https://hdl.handle.net/1721.1/132638