Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works Mechanisms of resistance to cancer immunotherapy remain poorly understood. Lymphocyte activation gene–3 (LAG3) signaling is regulated...

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Main Authors: Andrews, Lawrence P, Somasundaram, Ashwin, Moskovitz, Jessica M, Szymczak-Workman, Andrea L, Liu, Chang, Cillo, Anthony R, Lin, Huang, Normolle, Daniel P, Moynihan, Kelly Dare, Taniuchi, Ichiro, Irvine, Darrell J, Kirkwood, John M, Lipson, Evan J, Ferris, Robert L, Bruno, Tullia C, Workman, Creg J, Vignali, Dario AA
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/133023

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