Growth-Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging

Growth-Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging

© 2020 Elsevier Inc. Aminoacyl-tRNA synthetases (aaRSs) serve a dual role in charging tRNAs. Their enzymatic activities both provide protein synthesis flux and reduce uncharged tRNA levels. Although uncharged tRNAs can negatively impact bacterial growth, substantial concentrations of tRNAs remain de...

Full description

Bibliographic Details
Main Authors: Parker, Darren J., Lalanne, Jean-Benoit, Kimura, Satoshi, Johnson, Grace E., Waldor, Matthew K, Li, Gene-Wei
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/133026

Similar Items

Similar Items