S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus

© 2020 American Heart Association, Inc. Objective: Vascular calcification is a cardiovascular risk factor and accelerated in diabetes mellitus. Previous work has established a role for calcification-prone extracellular vesicles in promoting vascular calcification. However, the mechanisms by which di...

Full description

Bibliographic Details
Main Authors:	Kawakami, Ryo, Katsuki, Shunsuke, Travers, Richard, Romero, Dayanna Carolina, Becker-Greene, Dakota, Passos, Livia Silva Araujo, Higashi, Hideyuki, Blaser, Mark C, Sukhova, Galina K, Buttigieg, Josef, Kopriva, David, Schmidt, Ann Marie, Anderson, Daniel G, Singh, Sasha A, Cardoso, Luis, Weinbaum, Sheldon, Libby, Peter, Aikawa, Masanori, Croce, Kevin, Aikawa, Elena
Other Authors:	Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format:	Article
Language:	English
Published:	Ovid Technologies (Wolters Kluwer Health) 2021
Online Access:	https://hdl.handle.net/1721.1/133244

Similar Items

The effect of plaque morphology, material composition and microcalcifications on the risk of cap rupture: A structural analysis of vulnerable atherosclerotic plaques
by: Andrea Corti, et al.
Published: (2022-10-01)

Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification
by: Shinji Goto, et al.
Published: (2019-04-01)

Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification
by: Takeshi Tanaka, et al.
Published: (2022-01-01)

Identifying novel mechanisms of abdominal aortic aneurysm via unbiased proteomics and systems biology
by: Stephanie Morgan, et al.
Published: (2022-08-01)

Integration of Functional Imaging, Cytometry, and Unbiased Proteomics Reveals New Features of Endothelial-to-Mesenchymal Transition in Ischemic Mitral Valve Regurgitation in Human Patients
by: Adrien Lupieri, et al.
Published: (2021-08-01)

Dynamic Macrophages: Understanding Mechanisms of Activation as Guide to Therapy for Atherosclerotic Vascular Disease
by: Julius L. Decano, et al.
Published: (2018-08-01)

Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism
by: Mark C. Blaser, et al.
Published: (2018-12-01)

In silico Drug Screening Approach Using L1000-Based Connectivity Map and Its Application to COVID-19
by: Takaharu Asano, et al.
Published: (2022-03-01)

The RiboMaP Spectral Annotation Method Applied to Various ADP-Ribosylome Studies Including INF-γ-Stimulated Human Cells and Mouse Tissues
by: Sasha A. Singh, et al.
Published: (2022-03-01)

PARPs and ADP-Ribosylation in Chronic Inflammation: A Focus on Macrophages
by: Diego V. Santinelli-Pestana, et al.
Published: (2023-07-01)

The distinct metabolism between large and small HDL indicates unique origins of human apolipoprotein A4
by: Allison B. Andraski, et al.
Published: (2023-05-01)

Connections for Matters of the Heart: Network Medicine in Cardiovascular Diseases
by: Abhijeet Rajendra Sonawane, et al.
Published: (2022-05-01)

Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets
by: Joshua D. Hutcheson, et al.
Published: (2021-06-01)

Rage of angels /
by: Sheldon, Sidney, 1917-2007 author
Published: (1980)

Metabolism of PLTP, CETP, and LCAT on multiple HDL sizes using the Orbitrap Fusion Lumos
by: Sasha A. Singh, et al.
Published: (2021-02-01)

Gene Expression Profiling Reveals the Shared and Distinct Transcriptional Signatures in Human Lung Epithelial Cells Infected With SARS-CoV-2, MERS-CoV, or SARS-CoV: Potential Implications in Cardiovascular Complications of COVID-19
by: Prabhash Kumar Jha, et al.
Published: (2021-01-01)

Biomineralogical signatures of breast microcalcifications
by: Kunitake, Jennie AMR, et al.
Published: (2023)

Enrichment of calcifying extracellular vesicles using density-based ultracentrifugation protocol
by: Joshua D. Hutcheson, et al.
Published: (2014-12-01)

Proinflammatory Matrix Metalloproteinase-1 Associates With Mitral Valve Leaflet Disruption Following Percutaneous Mitral Valvuloplasty
by: Livia S. A. Passos, et al.
Published: (2022-01-01)

Raman spectroscopic sensing of carbonate intercalation in breast microcalcifications at stereotactic biopsy
by: Sathyavathi, R., et al.
Published: (2015)

Breast Cancer and Microcalcifications: An Osteoimmunological Disorder?
by: Alisson Clemenceau, et al.
Published: (2020-11-01)

Recurrent Placental Microcalcifications in the Second Trimester
by: Chun-Chieh Chia, et al.
Published: (2010-09-01)

N-acetylglucosamine-1-Phosphate Transferase Suppresses Lysosomal Hydrolases in Dysfunctional Osteoclasts: A Potential Mechanism for Vascular Calcification
by: Yang Lei, et al.
Published: (2015-04-01)

Induced pluripotent stem cell-derived smooth muscle cells to study cardiovascular calcification
by: Samantha K. Atkins, et al.
Published: (2022-07-01)

Accuracy of cone-beam computed tomography, digital mammography and digital breast tomosynthesis for microcalcifications and margins to microcalcifications in breast specimens
by: Claudia Neubauer, et al.
Published: (2022-10-01)

Management of patients with residual microcalcifications and false-negative results after stereotactic vacuum – assisted biopsy of mammographic suspicious microcalcifications
by: E. Georgiou, et al.
Published: (2021-04-01)

Classification of clusters of microcalcifications in digital breast tomosynthesis.
by: Ho, C, et al.
Published: (2010)

The reconstruction of microcalcification clusters in digital breast tomosynthesis
by: Ho, C, et al.
Published: (2010)

Evaluation of a decision aid for the classification of microcalcifications
by: Taylor, P, et al.
Published: (1998)

Coronary Artery Microcalcification: Imaging and Clinical Implications
by: Federico Vancheri, et al.
Published: (2019-09-01)

Detection of Masses and Microcalcifications in Digital Mammogram Images
by: Langarizadesh, Mostafa
Published: (2011)

Classification of Clustered Microcalcifications using MLFFBP-ANN and
by: Baljit Singh Khehra, et al.
Published: (2016-03-01)

Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms
by: Livia S. A. Passos, et al.
Published: (2021-01-01)

Assessment of EN-RAGE, sRAGE and EN-RAGE/sRAGE as potential biomarkers in patients with autoimmune hepatitis
by: Rui Wu, et al.
Published: (2020-10-01)

Development of High-Sensitivity Electrically Conductive Composite Elements by Press Molding of Polymer and Carbon Nanofibers
by: Shunsuke Aikawa, et al.
Published: (2022-01-01)

Ductal Carcinoma In Situ Underestimation of Microcalcifications Only by Stereotactic Vacuum-Assisted Breast Biopsy: A New Predictor of Specimens without Microcalcifications
by: Yun-Chung Cheung, et al.
Published: (2020-09-01)

Heart Valve Disease: Challenges and New Opportunities
by: Francesca Bartoli-Leonard, et al.
Published: (2020-10-01)

Rage /
by: 218351 Smith, Wilbur A.
Published: (1987)

Rage /
by: 218740 Kellerman, Jonathan
Published: (2006)

Microcalcifications segmentation using three edge detection techniques
by: Yasiran, Siti Salmah, et al.
Published: (2012)