Roadmap on biology in time varying environments
Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the gener...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2021
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| Online Access: | https://hdl.handle.net/1721.1/133264 |
| _version_ | 1826195558451118080 |
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| author | Murugan, Arvind Husain, Kabir Rust, Michael J Hepler, Chelsea Bass, Joseph Pietsch, Julian MJ Swain, Peter S Jena, Siddhartha G Toettcher, Jared E Chakraborty, Arup K Sprenger, Kayla G Mora, T Walczak, AM Rivoire, O Wang, Shenshen Wood, Kevin B Skanata, Antun Kussell, Edo Ranganathan, Rama Shih, Hong-yan Goldenfeld, Nigel |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Murugan, Arvind Husain, Kabir Rust, Michael J Hepler, Chelsea Bass, Joseph Pietsch, Julian MJ Swain, Peter S Jena, Siddhartha G Toettcher, Jared E Chakraborty, Arup K Sprenger, Kayla G Mora, T Walczak, AM Rivoire, O Wang, Shenshen Wood, Kevin B Skanata, Antun Kussell, Edo Ranganathan, Rama Shih, Hong-yan Goldenfeld, Nigel |
| author_sort | Murugan, Arvind |
| collection | MIT |
| description | Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the general principles by which organisms shape and are shaped by time varying environments remain elusive. Our understanding is particularly poor in the intermediate regime with no separation of timescales, where the environment changes on the same timescale as the physiological or evolutionary response. Experiments to systematically characterize the response to dynamic environments are challenging since such environments are inherently high dimensional. This roadmap deals with the unique role played by time varying environments in biological phenomena across scales, from physiology to evolution, seeking to emphasize the commonalities and the challenges faced in this emerging area of research. |
| first_indexed | 2024-09-23T10:14:36Z |
| format | Article |
| id | mit-1721.1/133264 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T10:14:36Z |
| publishDate | 2021 |
| publisher | IOP Publishing |
| record_format | dspace |
| spelling | mit-1721.1/1332642024-03-20T19:16:36Z Roadmap on biology in time varying environments Murugan, Arvind Husain, Kabir Rust, Michael J Hepler, Chelsea Bass, Joseph Pietsch, Julian MJ Swain, Peter S Jena, Siddhartha G Toettcher, Jared E Chakraborty, Arup K Sprenger, Kayla G Mora, T Walczak, AM Rivoire, O Wang, Shenshen Wood, Kevin B Skanata, Antun Kussell, Edo Ranganathan, Rama Shih, Hong-yan Goldenfeld, Nigel Massachusetts Institute of Technology. Department of Chemical Engineering Massachusetts Institute of Technology. Department of Physics Massachusetts Institute of Technology. Department of Chemistry Massachusetts Institute of Technology. Institute for Medical Engineering & Science Ragon Institute of MGH, MIT and Harvard Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the general principles by which organisms shape and are shaped by time varying environments remain elusive. Our understanding is particularly poor in the intermediate regime with no separation of timescales, where the environment changes on the same timescale as the physiological or evolutionary response. Experiments to systematically characterize the response to dynamic environments are challenging since such environments are inherently high dimensional. This roadmap deals with the unique role played by time varying environments in biological phenomena across scales, from physiology to evolution, seeking to emphasize the commonalities and the challenges faced in this emerging area of research. 2021-10-27T19:51:50Z 2021-10-27T19:51:50Z 2021 2021-06-08T17:57:37Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/133264 en 10.1088/1478-3975/abde8d Physical Biology Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf IOP Publishing IOP Publishing |
| spellingShingle | Murugan, Arvind Husain, Kabir Rust, Michael J Hepler, Chelsea Bass, Joseph Pietsch, Julian MJ Swain, Peter S Jena, Siddhartha G Toettcher, Jared E Chakraborty, Arup K Sprenger, Kayla G Mora, T Walczak, AM Rivoire, O Wang, Shenshen Wood, Kevin B Skanata, Antun Kussell, Edo Ranganathan, Rama Shih, Hong-yan Goldenfeld, Nigel Roadmap on biology in time varying environments |
| title | Roadmap on biology in time varying environments |
| title_full | Roadmap on biology in time varying environments |
| title_fullStr | Roadmap on biology in time varying environments |
| title_full_unstemmed | Roadmap on biology in time varying environments |
| title_short | Roadmap on biology in time varying environments |
| title_sort | roadmap on biology in time varying environments |
| url | https://hdl.handle.net/1721.1/133264 |
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