3D‐Printed Gastric Resident Electronics
© 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Long-term implantation of biomedical electronics into the human body enables advanced diagnostic and therapeutic functionalities. However, most long-term resident electronics devices require invasive procedures for imp...
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| Format: | Article |
| Language: | English |
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Wiley
2021
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| Online Access: | https://hdl.handle.net/1721.1/133291 |
| _version_ | 1826189510753386496 |
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| author | Kong, Yong Lin Zou, Xingyu McCandler, Caitlin A Kirtane, Ameya R Ning, Shen Zhou, Jianlin Abid, Abubakar Jafari, Mousa Rogner, Jaimie Minahan, Daniel Collins, Joy E McDonnell, Shane Cleveland, Cody Bensel, Taylor Tamang, Siid Arrick, Graham Gimbel, Alla Hua, Tiffany Ghosh, Udayan Soares, Vance Wang, Nancy Wahane, Aniket Hayward, Alison Zhang, Shiyi Smith, Brian R Langer, Robert Traverso, Giovanni |
| author_facet | Kong, Yong Lin Zou, Xingyu McCandler, Caitlin A Kirtane, Ameya R Ning, Shen Zhou, Jianlin Abid, Abubakar Jafari, Mousa Rogner, Jaimie Minahan, Daniel Collins, Joy E McDonnell, Shane Cleveland, Cody Bensel, Taylor Tamang, Siid Arrick, Graham Gimbel, Alla Hua, Tiffany Ghosh, Udayan Soares, Vance Wang, Nancy Wahane, Aniket Hayward, Alison Zhang, Shiyi Smith, Brian R Langer, Robert Traverso, Giovanni |
| author_sort | Kong, Yong Lin |
| collection | MIT |
| description | © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Long-term implantation of biomedical electronics into the human body enables advanced diagnostic and therapeutic functionalities. However, most long-term resident electronics devices require invasive procedures for implantation as well as a specialized receiver for communication. Here, a gastric resident electronic (GRE) system that leverages the anatomical space offered by the gastric environment to enable residence of an orally delivered platform of such devices within the human body is presented. The GRE is capable of directly interfacing with portable consumer personal electronics through Bluetooth, a widely adopted wireless protocol. In contrast to the passive day-long gastric residence achieved with prior ingestible electronics, advancement in multimaterial prototyping enables the GRE to reside in the hostile gastric environment for a maximum of 36 d and maintain ≈15 d of wireless electronics communications as evidenced by the studies in a porcine model. Indeed, the synergistic integration of reconfigurable gastric-residence structure, drug release modules, and wireless electronics could ultimately enable the next-generation remote diagnostic and automated therapeutic strategies. |
| first_indexed | 2024-09-23T08:16:19Z |
| format | Article |
| id | mit-1721.1/133291 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T08:16:19Z |
| publishDate | 2021 |
| publisher | Wiley |
| record_format | dspace |
| spelling | mit-1721.1/1332912022-03-31T14:31:25Z 3D‐Printed Gastric Resident Electronics Kong, Yong Lin Zou, Xingyu McCandler, Caitlin A Kirtane, Ameya R Ning, Shen Zhou, Jianlin Abid, Abubakar Jafari, Mousa Rogner, Jaimie Minahan, Daniel Collins, Joy E McDonnell, Shane Cleveland, Cody Bensel, Taylor Tamang, Siid Arrick, Graham Gimbel, Alla Hua, Tiffany Ghosh, Udayan Soares, Vance Wang, Nancy Wahane, Aniket Hayward, Alison Zhang, Shiyi Smith, Brian R Langer, Robert Traverso, Giovanni © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Long-term implantation of biomedical electronics into the human body enables advanced diagnostic and therapeutic functionalities. However, most long-term resident electronics devices require invasive procedures for implantation as well as a specialized receiver for communication. Here, a gastric resident electronic (GRE) system that leverages the anatomical space offered by the gastric environment to enable residence of an orally delivered platform of such devices within the human body is presented. The GRE is capable of directly interfacing with portable consumer personal electronics through Bluetooth, a widely adopted wireless protocol. In contrast to the passive day-long gastric residence achieved with prior ingestible electronics, advancement in multimaterial prototyping enables the GRE to reside in the hostile gastric environment for a maximum of 36 d and maintain ≈15 d of wireless electronics communications as evidenced by the studies in a porcine model. Indeed, the synergistic integration of reconfigurable gastric-residence structure, drug release modules, and wireless electronics could ultimately enable the next-generation remote diagnostic and automated therapeutic strategies. 2021-10-27T19:51:57Z 2021-10-27T19:51:57Z 2019 2019-09-06T19:43:50Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/133291 en 10.1002/ADMT.201800490 Advanced Materials Technologies Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Wiley Wiley |
| spellingShingle | Kong, Yong Lin Zou, Xingyu McCandler, Caitlin A Kirtane, Ameya R Ning, Shen Zhou, Jianlin Abid, Abubakar Jafari, Mousa Rogner, Jaimie Minahan, Daniel Collins, Joy E McDonnell, Shane Cleveland, Cody Bensel, Taylor Tamang, Siid Arrick, Graham Gimbel, Alla Hua, Tiffany Ghosh, Udayan Soares, Vance Wang, Nancy Wahane, Aniket Hayward, Alison Zhang, Shiyi Smith, Brian R Langer, Robert Traverso, Giovanni 3D‐Printed Gastric Resident Electronics |
| title | 3D‐Printed Gastric Resident Electronics |
| title_full | 3D‐Printed Gastric Resident Electronics |
| title_fullStr | 3D‐Printed Gastric Resident Electronics |
| title_full_unstemmed | 3D‐Printed Gastric Resident Electronics |
| title_short | 3D‐Printed Gastric Resident Electronics |
| title_sort | 3d printed gastric resident electronics |
| url | https://hdl.handle.net/1721.1/133291 |
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