DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7
© 2021, eLife Sciences Publications Ltd. All rights reserved. The committed step of eukaryotic DNA replication occurs when the pairs of Mcm2-7 replicative helicases that license each replication origin are activated. Helicase activation requires the recruitment of Cdc45 and GINS to Mcm2-7, forming C...
Main Authors: | De Jesús-Kim, Lorraine, Friedman, Larry J, Lõoke, Marko, Ramsoomair, Christian K, Gelles, Jeff, Bell, Stephen P |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2021
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Online Access: | https://hdl.handle.net/1721.1/133327 |
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