Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity

© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc. The Rbfox family of splicing factors regulate alternative splicing during animal development and in disease, impacting thousands of exons in the maturing brain, heart and muscle. Rbfox proteins have long been known to bi...

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Bibliographic Details
Main Authors: Begg, Bridget E, Jens, Marvin, Wang, Peter Y, Minor, Christine M, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133385