Inducing DNA damage through R-loops to kill cancer cells
© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. R-loops are intermediate structures of transcription that can accumulate when transcriptional elongation is blocked by inhibiting BRD4. In normal cells, R-loop persistence suppresses firing of adjacent replication ori...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Informa UK Limited
2021
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| Online Access: | https://hdl.handle.net/1721.1/133481 |