Clinically relevant mutations in core metabolic genes confer antibiotic resistance

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

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© 2021 American Association for the Advancement of Science. All rights reserved. Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is generally associated with drug target modification, enzymatic inactivation, and/or transport rather than metabolic processes. Ev...

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Bibliographic Details
Main Authors: Lopatkin, Allison J, Bening, Sarah C, Manson, Abigail L, Stokes, Jonathan M, Kohanski, Michael A, Badran, Ahmed H, Earl, Ashlee M, Cheney, Nicole J, Yang, Jason H, Collins, James J
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/133494

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