Co-evolution and Co-speciation of Host-Gut Bacteria Systems
© 2020 The Authors Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive the evolution of host-microbiome systems are poorly understood. Recent studies suggest that mammals and their individual gut symbionts can have parallel evolutionary histories, as represented...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV
2022
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| Online Access: | https://hdl.handle.net/1721.1/133505.2 |
| _version_ | 1810999716480024576 |
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| author | Groussin, Mathieu Mazel, Florent Alm, Eric J. |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Groussin, Mathieu Mazel, Florent Alm, Eric J. |
| author_sort | Groussin, Mathieu |
| collection | MIT |
| description | © 2020 The Authors Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive the evolution of host-microbiome systems are poorly understood. Recent studies suggest that mammals and their individual gut symbionts can have parallel evolutionary histories, as represented by their congruent phylogenies. These “co-phylogenetic” patterns are signatures of ancient co-speciation events and illustrate the cohesiveness of the mammalian host-gut microbiome entity over evolutionary times. Theory predicts that co-speciation between mammals and their gut symbionts could result from their co-evolution. However, there is only limited evidence of such co-evolution. Here, we propose a model that explains cophylogenetic patterns without relying on co-evolution. Specifically, we suggest that individual gut bacteria are likely to diverge in patterns recapitulating host phylogeny when hosts undergo allopatric speciation, limiting inter-host bacterial dispersal and genomic recombination. We provide evidence that the model is empirically grounded and propose a series of observational and experimental approaches to test its validity. |
| first_indexed | 2024-09-23T15:05:16Z |
| format | Article |
| id | mit-1721.1/133505.2 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T15:05:16Z |
| publishDate | 2022 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/133505.22024-06-14T15:26:51Z Co-evolution and Co-speciation of Host-Gut Bacteria Systems Groussin, Mathieu Mazel, Florent Alm, Eric J. Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics © 2020 The Authors Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive the evolution of host-microbiome systems are poorly understood. Recent studies suggest that mammals and their individual gut symbionts can have parallel evolutionary histories, as represented by their congruent phylogenies. These “co-phylogenetic” patterns are signatures of ancient co-speciation events and illustrate the cohesiveness of the mammalian host-gut microbiome entity over evolutionary times. Theory predicts that co-speciation between mammals and their gut symbionts could result from their co-evolution. However, there is only limited evidence of such co-evolution. Here, we propose a model that explains cophylogenetic patterns without relying on co-evolution. Specifically, we suggest that individual gut bacteria are likely to diverge in patterns recapitulating host phylogeny when hosts undergo allopatric speciation, limiting inter-host bacterial dispersal and genomic recombination. We provide evidence that the model is empirically grounded and propose a series of observational and experimental approaches to test its validity. 2022-03-17T14:39:46Z 2021-10-27T19:53:12Z 2022-03-17T14:39:46Z 2020-07 2021-08-24T17:00:25Z Article http://purl.org/eprint/type/JournalArticle 1931-3128 https://hdl.handle.net/1721.1/133505.2 en http://dx.doi.org/10.1016/j.chom.2020.06.013 Cell Host & Microbe Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/octet-stream Elsevier BV Elsevier |
| spellingShingle | Groussin, Mathieu Mazel, Florent Alm, Eric J. Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title | Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title_full | Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title_fullStr | Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title_full_unstemmed | Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title_short | Co-evolution and Co-speciation of Host-Gut Bacteria Systems |
| title_sort | co evolution and co speciation of host gut bacteria systems |
| url | https://hdl.handle.net/1721.1/133505.2 |
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