Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

© 2020, The Author(s). Following immunization, high-affinity antibody responses develop within germinal centers (GCs), specialized sites within follicles of the lymph node (LN) where B cells proliferate and undergo somatic hypermutation. Antigen availability within GCs is important, as B cells must...

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Bibliographic Details
Main Authors: Martin, Jacob T, Cottrell, Christopher A, Antanasijevic, Aleksandar, Carnathan, Diane G, Cossette, Benjamin J, Enemuo, Chiamaka A, Gebru, Etse H, Choe, Yury, Viviano, Federico, Fischinger, Stephanie, Tokatlian, Talar, Cirelli, Kimberly M, Ueda, George, Copps, Jeffrey, Schiffner, Torben, Menis, Sergey, Alter, Galit, Schief, William R, Crotty, Shane, King, Neil P, Baker, David, Silvestri, Guido, Ward, Andrew B, Irvine, Darrell J
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133531

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