Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

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© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA methylome, hydroxymethylome, and transcriptome analyses were co...

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Bibliographic Details
Main Authors: Han, Qiyuan, Kono, Thomas JY, Knutson, Charles G, Parry, Nicola M, Seiler, Christopher L, Fox, James G, Tannenbaum, Steven R, Tretyakova, Natalia Y
Format: Article
Language:English
Published: MDPI AG 2021
Online Access:https://hdl.handle.net/1721.1/133596

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