Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells

Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells

Show other versions (1)

© 2020 The Authors Background & Aims: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction complex, claudin-18 localizes mainly to the basolateral membrane where its contribution to paracellu...

Full description

Bibliographic Details
Main Authors:	Caron, Tyler J, Scott, Kathleen E, Sinha, Nishita, Muthupalani, Sureshkumar, Baqai, Mahnoor, Ang, Lay-Hong, Li, Yue, Turner, Jerrold R, Fox, James G, Hagen, Susan J
Format:	Article
Language:	English
Published:	Elsevier BV 2021
Online Access:	https://hdl.handle.net/1721.1/133612

Similar Items

Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells
by: Caron, Tyler J, et al.
Published: (2022)

Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
by: Hagen, Susan J., et al.
Published: (2018)

Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach
by: Hagen, Susan J., et al.
Published: (2020)

Effect of Lactic Acid Bacteria on the Intestinal Structure and the Expression of Ileal Tight Junction Molecule Claudins in Broiler
by: Ariyadi, Bambang, et al.
Published: (2014)

Claudin expression and tight junction protein localization in the lining epithelium of the keratocystic odontogenic tumors, dentigerous cysts, and radicular cysts
by: Siar, C.H., et al.
Published: (2013)

Function of ArhGAP12 in the assembly and regulation of epithelial tight junctions
by: Tambrin, Hana Maldivita
Published: (2024)

Expression of tight junction molecule “claudins” in the lower oviductal segments and their changes with egg-laying phase and gonadal steroid stimulation in hens.
by: Ariyadi, Bambang, et al.
Published: (2013)

The mammalian crumbs complex defines a distinct polarity domain apical of epithelial tight junctions
by: Tan, Benedict, et al.
Published: (2020)

PALS1 is a key regulator of the lateral distribution of tight junction proteins in renal epithelial cells
by: Groh, Ann-Christin, et al.
Published: (2024)

Interferon-γ inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T cell apoptosis
by: Tu, Shui Ping, et al.
Published: (2012)

Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
by: Assi, Reem Abou
Published: (2018)

Investigating tight junction proteinrelated regulation of nasal epithelial barrier integrity in allergic rhinitis patients and non-allergic individuals
by: Othman, Siti Sarah Che
Published: (2023)

An on-chip model of protein paracellular and transcellular permeability in the microcirculation
by: Offeddu, Giovanni, et al.
Published: (2020)

The effect of ECM materials on tight junction proteins
by: Vu, Dung Le
Published: (2015)

Targeting the tight junction : immunotherapy of colon cancer
by: Ackerman, Margaret E
Published: (2011)

Stromal cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors
by: Shibata, Wataru, et al.
Published: (2012)

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
by: Taube, Joseph H., et al.
Published: (2014)

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters
by: Huang, Royston-Luke, et al.
Published: (2011)

Mouse Models of Gastric Cancer
by: Hayakawa, Yoku, et al.
Published: (2018)

Elucidation of clinical, environmental and T helper 2 factors on tight junction expressions in allergic rhinitis
by: Muhamad, Siti Nur Husna
Published: (2022)

Laparoscopic sleeve gastrectomy for oesophago-gastric junction duplication cyst and morbid obesity
by: Gee, Tikfu, et al.
Published: (2020)

Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota
by: Whary, Mark T., et al.
Published: (2015)

Transmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells
by: Franke, Werner W., et al.
Published: (2013)

Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia
by: Muthupalani, Sureshkumar, et al.
Published: (2020)

Mesoscopic dynamic model of epithelial cell division with cell-cell junction effects
by: Liu, Zong-Yuan, et al.
Published: (2021)

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis
by: Lertpiriyapong, Kvin, et al.
Published: (2014)

Denervation suppresses gastric tumorigenesis
by: Zhao, Chun-Mei, et al.
Published: (2015)

Attenuation of H-Pylori-Induced Gastric Pathology in C57bl/6 Mice by Co-Infection with Enterohepatic Helicobacters Is Helicobacter Species-Dependent
by: Ge, Zhongming, et al.
Published: (2013)

An EMT–primary cilium–GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
by: Wilson, Molly M, et al.
Published: (2022)

Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway
by: Hu, Yi, et al.
Published: (2018)

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes
by: Hasegawa, Kazuhiro, et al.
Published: (2015)

An evaluation of tight-pitch PWR cores
by: Correa, Francisco, et al.
Published: (2006)

UUM finance tight
by: Sin Chiew, Daily
Published: (2011)

A Combination of Sulindac and Antimicrobial Eradication of H. pylori Prevents Progression of Gastric Cancer in Hypergastrinemic INS-GAS Mice
by: Lee, Chung-Wei, et al.
Published: (2012)

Pathways for mechanotransduction in pressurized airway epithelial cells
by: McVittie, Anna K. (Anna Kathleen), 1977-
Published: (2014)

Conditional Deletion of IkappaB-Kinase-beta Accelerates Helicobacter-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia
by: Shibata, Wataru, et al.
Published: (2011)

N-methyl d-Aspartate Channels Link Ammonia and Epithelial Cell Death Mechanisms in Helicobacter pylori Infection
by: Seo, Ji Hye, et al.
Published: (2018)

Helicobacter pylori-infected C57BL/6 mice with different gastrointestinal microbiota have contrasting gastric pathology, microbial and host immune responses
by: Ge, Zhongming, et al.
Published: (2018)

Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response
by: Ericksen, Russell E., et al.
Published: (2014)

Keeping a tight leash on education
by: Abd Razak, Dzulkifli
Published: (2008)