Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus
© 2020 National Academy of Sciences. All rights reserved. The fusiform face area responds selectively to faces and is causally involved in face perception. How does face-selectivity in the fusiform arise in development, and why does it develop so systematically in the same location across individual...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Proceedings of the National Academy of Sciences
2021
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| Online Access: | https://hdl.handle.net/1721.1/133966 |
| _version_ | 1811083759180578816 |
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| author | Ratan Murty, N Apurva Teng, Santani Beeler, David Mynick, Anna Oliva, Aude Kanwisher, Nancy |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Ratan Murty, N Apurva Teng, Santani Beeler, David Mynick, Anna Oliva, Aude Kanwisher, Nancy |
| author_sort | Ratan Murty, N Apurva |
| collection | MIT |
| description | © 2020 National Academy of Sciences. All rights reserved. The fusiform face area responds selectively to faces and is causally involved in face perception. How does face-selectivity in the fusiform arise in development, and why does it develop so systematically in the same location across individuals? Preferential cortical responses to faces develop early in infancy, yet evidence is conflicting on the central question of whether visual experience with faces is necessary. Here, we revisit this question by scanning congenitally blind individuals with fMRI while they haptically explored 3D-printed faces and other stimuli. We found robust face-selective responses in the lateral fusiform gyrus of individual blind participants during haptic exploration of stimuli, indicating that neither visual experience with faces nor fovea-biased inputs is necessary for face-selectivity to arise in the lateral fusiform gyrus. Our results instead suggest a role for long-range connectivity in specifying the location of face-selectivity in the human brain. |
| first_indexed | 2024-09-23T12:38:36Z |
| format | Article |
| id | mit-1721.1/133966 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T12:38:36Z |
| publishDate | 2021 |
| publisher | Proceedings of the National Academy of Sciences |
| record_format | dspace |
| spelling | mit-1721.1/1339662023-09-12T20:06:01Z Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus Ratan Murty, N Apurva Teng, Santani Beeler, David Mynick, Anna Oliva, Aude Kanwisher, Nancy Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT Center for Brains, Minds, and Machines Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory © 2020 National Academy of Sciences. All rights reserved. The fusiform face area responds selectively to faces and is causally involved in face perception. How does face-selectivity in the fusiform arise in development, and why does it develop so systematically in the same location across individuals? Preferential cortical responses to faces develop early in infancy, yet evidence is conflicting on the central question of whether visual experience with faces is necessary. Here, we revisit this question by scanning congenitally blind individuals with fMRI while they haptically explored 3D-printed faces and other stimuli. We found robust face-selective responses in the lateral fusiform gyrus of individual blind participants during haptic exploration of stimuli, indicating that neither visual experience with faces nor fovea-biased inputs is necessary for face-selectivity to arise in the lateral fusiform gyrus. Our results instead suggest a role for long-range connectivity in specifying the location of face-selectivity in the human brain. 2021-10-27T19:57:25Z 2021-10-27T19:57:25Z 2020 2021-03-19T12:26:57Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/133966 en 10.1073/PNAS.2004607117 Proceedings of the National Academy of Sciences of the United States of America Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Proceedings of the National Academy of Sciences PNAS |
| spellingShingle | Ratan Murty, N Apurva Teng, Santani Beeler, David Mynick, Anna Oliva, Aude Kanwisher, Nancy Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title | Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title_full | Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title_fullStr | Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title_full_unstemmed | Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title_short | Visual experience is not necessary for the development of face-selectivity in the lateral fusiform gyrus |
| title_sort | visual experience is not necessary for the development of face selectivity in the lateral fusiform gyrus |
| url | https://hdl.handle.net/1721.1/133966 |
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