The biosecurity benefits of genetic engineering attribution
© 2020, The Author(s). Biology can be misused, and the risk of this causing widespread harm increases in step with the rapid march of technological progress. A key security challenge involves attribution: determining, in the wake of a human-caused biological event, who was responsible. Recent scient...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC
2021
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| Online Access: | https://hdl.handle.net/1721.1/134114 |
| _version_ | 1811075878562562048 |
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| author | Lewis, Gregory Jordan, Jacob L Relman, David A Koblentz, Gregory D Leung, Jade Dafoe, Allan Nelson, Cassidy Epstein, Gerald L Katz, Rebecca Montague, Michael Alley, Ethan C Filone, Claire Marie Luby, Stephen Church, George M Millett, Piers Esvelt, Kevin M Cameron, Elizabeth E Inglesby, Thomas V |
| author2 | Massachusetts Institute of Technology. Media Laboratory |
| author_facet | Massachusetts Institute of Technology. Media Laboratory Lewis, Gregory Jordan, Jacob L Relman, David A Koblentz, Gregory D Leung, Jade Dafoe, Allan Nelson, Cassidy Epstein, Gerald L Katz, Rebecca Montague, Michael Alley, Ethan C Filone, Claire Marie Luby, Stephen Church, George M Millett, Piers Esvelt, Kevin M Cameron, Elizabeth E Inglesby, Thomas V |
| author_sort | Lewis, Gregory |
| collection | MIT |
| description | © 2020, The Author(s). Biology can be misused, and the risk of this causing widespread harm increases in step with the rapid march of technological progress. A key security challenge involves attribution: determining, in the wake of a human-caused biological event, who was responsible. Recent scientific developments have demonstrated a capability for detecting whether an organism involved in such an event has been genetically modified and, if modified, to infer from its genetic sequence its likely lab of origin. We believe this technique could be developed into powerful forensic tools to aid the attribution of outbreaks caused by genetically engineered pathogens, and thus protect against the potential misuse of synthetic biology. |
| first_indexed | 2024-09-23T10:13:13Z |
| format | Article |
| id | mit-1721.1/134114 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T10:13:13Z |
| publishDate | 2021 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1341142023-02-23T15:24:44Z The biosecurity benefits of genetic engineering attribution Lewis, Gregory Jordan, Jacob L Relman, David A Koblentz, Gregory D Leung, Jade Dafoe, Allan Nelson, Cassidy Epstein, Gerald L Katz, Rebecca Montague, Michael Alley, Ethan C Filone, Claire Marie Luby, Stephen Church, George M Millett, Piers Esvelt, Kevin M Cameron, Elizabeth E Inglesby, Thomas V Massachusetts Institute of Technology. Media Laboratory © 2020, The Author(s). Biology can be misused, and the risk of this causing widespread harm increases in step with the rapid march of technological progress. A key security challenge involves attribution: determining, in the wake of a human-caused biological event, who was responsible. Recent scientific developments have demonstrated a capability for detecting whether an organism involved in such an event has been genetically modified and, if modified, to infer from its genetic sequence its likely lab of origin. We believe this technique could be developed into powerful forensic tools to aid the attribution of outbreaks caused by genetically engineered pathogens, and thus protect against the potential misuse of synthetic biology. 2021-10-27T19:58:11Z 2021-10-27T19:58:11Z 2020 2021-06-23T16:20:35Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134114 en 10.1038/s41467-020-19149-2 Nature Communications Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Springer Science and Business Media LLC Nature |
| spellingShingle | Lewis, Gregory Jordan, Jacob L Relman, David A Koblentz, Gregory D Leung, Jade Dafoe, Allan Nelson, Cassidy Epstein, Gerald L Katz, Rebecca Montague, Michael Alley, Ethan C Filone, Claire Marie Luby, Stephen Church, George M Millett, Piers Esvelt, Kevin M Cameron, Elizabeth E Inglesby, Thomas V The biosecurity benefits of genetic engineering attribution |
| title | The biosecurity benefits of genetic engineering attribution |
| title_full | The biosecurity benefits of genetic engineering attribution |
| title_fullStr | The biosecurity benefits of genetic engineering attribution |
| title_full_unstemmed | The biosecurity benefits of genetic engineering attribution |
| title_short | The biosecurity benefits of genetic engineering attribution |
| title_sort | biosecurity benefits of genetic engineering attribution |
| url | https://hdl.handle.net/1721.1/134114 |
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