Towards a Human Cell Atlas: Taking Notes from the Past
Comprehensively characterizing the cellular composition and organization of tissues has been a long-term scientific challenge that has limited our ability to study fundamental and clinical aspects of human physiology. The Human Cell Atlas (HCA) is a global collaborative effort to create a reference...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV
2021
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| Online Access: | https://hdl.handle.net/1721.1/134116 |
| _version_ | 1811086165860679680 |
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| author | Lindeboom, Rik GH Regev, Aviv Teichmann, Sarah A |
| author_facet | Lindeboom, Rik GH Regev, Aviv Teichmann, Sarah A |
| author_sort | Lindeboom, Rik GH |
| collection | MIT |
| description | Comprehensively characterizing the cellular composition and organization of tissues has been a long-term scientific challenge that has limited our ability to study fundamental and clinical aspects of human physiology. The Human Cell Atlas (HCA) is a global collaborative effort to create a reference map of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease. Many aspects of the HCA are analogous to the Human Genome Project (HGP), whose completion presents a major milestone in modern biology. To commemorate the HGP's 20-year anniversary of completion, we discuss the launch of the HCA in light of the HGP, and highlight recent progress by the HCA consortium. |
| first_indexed | 2024-09-23T13:21:51Z |
| format | Article |
| id | mit-1721.1/134116 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:21:51Z |
| publishDate | 2021 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1341162021-10-28T03:53:13Z Towards a Human Cell Atlas: Taking Notes from the Past Lindeboom, Rik GH Regev, Aviv Teichmann, Sarah A Comprehensively characterizing the cellular composition and organization of tissues has been a long-term scientific challenge that has limited our ability to study fundamental and clinical aspects of human physiology. The Human Cell Atlas (HCA) is a global collaborative effort to create a reference map of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease. Many aspects of the HCA are analogous to the Human Genome Project (HGP), whose completion presents a major milestone in modern biology. To commemorate the HGP's 20-year anniversary of completion, we discuss the launch of the HCA in light of the HGP, and highlight recent progress by the HCA consortium. 2021-10-27T19:58:12Z 2021-10-27T19:58:12Z 2021 2021-07-23T16:44:03Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134116 en 10.1016/j.tig.2021.03.007 Trends in Genetics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. https://creativecommons.org/licenses/by/4.0/ application/pdf Elsevier BV Elsevier |
| spellingShingle | Lindeboom, Rik GH Regev, Aviv Teichmann, Sarah A Towards a Human Cell Atlas: Taking Notes from the Past |
| title | Towards a Human Cell Atlas: Taking Notes from the Past |
| title_full | Towards a Human Cell Atlas: Taking Notes from the Past |
| title_fullStr | Towards a Human Cell Atlas: Taking Notes from the Past |
| title_full_unstemmed | Towards a Human Cell Atlas: Taking Notes from the Past |
| title_short | Towards a Human Cell Atlas: Taking Notes from the Past |
| title_sort | towards a human cell atlas taking notes from the past |
| url | https://hdl.handle.net/1721.1/134116 |
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