Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations

© Bury et al. Although originally thought to be silent chromosomal regions, centromeres are instead actively transcribed. However, the behavior and contributions of centromere-derived RNAs have remained unclear. Here, we used single-molecule fluorescence in-situ hybridization (smFISH) to detect alph...

Full description

Bibliographic Details
Main Authors: Bury, Leah, Moodie, Brittania, Ly, Jimmy, McKay, Liliana S, Miga, Karen HH, Cheeseman, Iain M
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2021
Online Access:https://hdl.handle.net/1721.1/134140

Similar Items