Advances in oligonucleotide drug delivery
Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these molecules have potential therapeutic applicat...
Main Authors: | Roberts, Thomas C, Langer, Robert, Wood, Matthew JA |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2021
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Online Access: | https://hdl.handle.net/1721.1/134149 |
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