A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers
3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from a material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing the gel pH to induce dissolution. This process is performed in an entir...
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Format: | Article |
Language: | English |
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Wiley
2021
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Online Access: | https://hdl.handle.net/1721.1/134515 |
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author | Bellan, Leon M Pearsall, Matthew Cropek, Donald M Langer, Robert |
author_facet | Bellan, Leon M Pearsall, Matthew Cropek, Donald M Langer, Robert |
author_sort | Bellan, Leon M |
collection | MIT |
description | 3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from a material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing the gel pH to induce dissolution. This process is performed in an entirely aqueous environment, avoiding extreme temperatures, low pressures, and toxic organic solvents. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
first_indexed | 2024-09-23T13:37:37Z |
format | Article |
id | mit-1721.1/134515 |
institution | Massachusetts Institute of Technology |
language | English |
last_indexed | 2024-09-23T13:37:37Z |
publishDate | 2021 |
publisher | Wiley |
record_format | dspace |
spelling | mit-1721.1/1345152022-03-29T20:43:01Z A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers Bellan, Leon M Pearsall, Matthew Cropek, Donald M Langer, Robert 3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from a material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing the gel pH to induce dissolution. This process is performed in an entirely aqueous environment, avoiding extreme temperatures, low pressures, and toxic organic solvents. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 2021-10-27T20:05:22Z 2021-10-27T20:05:22Z 2012 2019-09-04T17:25:10Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134515 Bellan, L. M., et al. "A 3d Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers." Adv Mater (2012). en 10.1002/adma.201200810 Advanced Materials Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley PMC |
spellingShingle | Bellan, Leon M Pearsall, Matthew Cropek, Donald M Langer, Robert A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title | A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title_full | A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title_fullStr | A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title_full_unstemmed | A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title_short | A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers |
title_sort | 3d interconnected microchannel network formed in gelatin by sacrificial shellac microfibers |
url | https://hdl.handle.net/1721.1/134515 |
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