Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries
A simple method to control spatial organizations of multiple cell types in predefined geometries by using poly(N-isopropylacrylamide)-based dynamic microwells is described. Dynamic microwells are used to pattern two different cell types in a spatially controlled manner by exploiting their shape chan...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021
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| Online Access: | https://hdl.handle.net/1721.1/134516 |
| _version_ | 1826207563890294784 |
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| author | Tekin, Halil Sanchez, Jefferson G Landeros, Christian Dubbin, Karen Langer, Robert Khademhosseini, Ali |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Tekin, Halil Sanchez, Jefferson G Landeros, Christian Dubbin, Karen Langer, Robert Khademhosseini, Ali |
| author_sort | Tekin, Halil |
| collection | MIT |
| description | A simple method to control spatial organizations of multiple cell types in predefined geometries by using poly(N-isopropylacrylamide)-based dynamic microwells is described. Dynamic microwells are used to pattern two different cell types in a spatially controlled manner by exploiting their shape changing properties at two different temperatures. Both spatial organization of two different cell types and control of pattern geometry are achieved with circular and square dynamic microwells. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| first_indexed | 2024-09-23T13:51:30Z |
| format | Article |
| id | mit-1721.1/134516 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:51:30Z |
| publishDate | 2021 |
| publisher | Wiley |
| record_format | dspace |
| spelling | mit-1721.1/1345162023-02-17T16:07:35Z Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries Tekin, Halil Sanchez, Jefferson G Landeros, Christian Dubbin, Karen Langer, Robert Khademhosseini, Ali Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Koch Institute for Integrative Cancer Research at MIT Massachusetts Institute of Technology. Department of Chemical Engineering Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Materials Science and Engineering A simple method to control spatial organizations of multiple cell types in predefined geometries by using poly(N-isopropylacrylamide)-based dynamic microwells is described. Dynamic microwells are used to pattern two different cell types in a spatially controlled manner by exploiting their shape changing properties at two different temperatures. Both spatial organization of two different cell types and control of pattern geometry are achieved with circular and square dynamic microwells. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 2021-10-27T20:05:22Z 2021-10-27T20:05:22Z 2012 2019-09-04T17:27:33Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134516 Tekin, H., et al. "Controlling Spatial Organization of Multiple Cell Types in Defined 3d Geometries." Adv Mater (2012). en 10.1002/adma.201201805 Advanced Materials Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley PMC |
| spellingShingle | Tekin, Halil Sanchez, Jefferson G Landeros, Christian Dubbin, Karen Langer, Robert Khademhosseini, Ali Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title | Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title_full | Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title_fullStr | Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title_full_unstemmed | Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title_short | Controlling Spatial Organization of Multiple Cell Types in Defined 3D Geometries |
| title_sort | controlling spatial organization of multiple cell types in defined 3d geometries |
| url | https://hdl.handle.net/1721.1/134516 |
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