Microgels for Efficient Protein Purification

Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient...

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Main Authors: Mizrahi, Boaz, Irusta, Silvia, McKenna, Marshall, Stefanescu, Cristina, Yedidsion, Liron, Myint, MyatNoeZin, Langer, Robert, Kohane, Daniel S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Wiley 2021
Online Access:https://hdl.handle.net/1721.1/134518
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author Mizrahi, Boaz
Irusta, Silvia
McKenna, Marshall
Stefanescu, Cristina
Yedidsion, Liron
Myint, MyatNoeZin
Langer, Robert
Kohane, Daniel S
author2 Massachusetts Institute of Technology. Department of Chemical Engineering
author_facet Massachusetts Institute of Technology. Department of Chemical Engineering
Mizrahi, Boaz
Irusta, Silvia
McKenna, Marshall
Stefanescu, Cristina
Yedidsion, Liron
Myint, MyatNoeZin
Langer, Robert
Kohane, Daniel S
author_sort Mizrahi, Boaz
collection MIT
description Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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spelling mit-1721.1/1345182023-01-20T20:32:14Z Microgels for Efficient Protein Purification Mizrahi, Boaz Irusta, Silvia McKenna, Marshall Stefanescu, Cristina Yedidsion, Liron Myint, MyatNoeZin Langer, Robert Kohane, Daniel S Massachusetts Institute of Technology. Department of Chemical Engineering Massachusetts Institute of Technology. Operations Research Center Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 2021-10-27T20:05:23Z 2021-10-27T20:05:23Z 2011 2019-09-04T17:13:26Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134518 Mizrahi, B., et al. "Microgels for Efficient Protein Purification." Adv Mater (2011). en 10.1002/adma.201101258 Advanced Materials Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley PMC
spellingShingle Mizrahi, Boaz
Irusta, Silvia
McKenna, Marshall
Stefanescu, Cristina
Yedidsion, Liron
Myint, MyatNoeZin
Langer, Robert
Kohane, Daniel S
Microgels for Efficient Protein Purification
title Microgels for Efficient Protein Purification
title_full Microgels for Efficient Protein Purification
title_fullStr Microgels for Efficient Protein Purification
title_full_unstemmed Microgels for Efficient Protein Purification
title_short Microgels for Efficient Protein Purification
title_sort microgels for efficient protein purification
url https://hdl.handle.net/1721.1/134518
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