Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial
© 2020 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. Mindfulness training can enhance cognitive control, but the neural mechanisms underlying such enhancement in children are unknown. Here, we conducted a randomized controlled trial (RCT) with sixth graders (mean age 11.76 yea...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021
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| Online Access: | https://hdl.handle.net/1721.1/134562 |
| _version_ | 1826203458359787520 |
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| author | Bauer, Clemens CC Rozenkrantz, Liron Caballero, Camila Nieto-Castanon, Alfonso Scherer, Ethan West, Martin R Mrazek, Michael Phillips, Dawa T Gabrieli, John DE Whitfield-Gabrieli, Susan |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Bauer, Clemens CC Rozenkrantz, Liron Caballero, Camila Nieto-Castanon, Alfonso Scherer, Ethan West, Martin R Mrazek, Michael Phillips, Dawa T Gabrieli, John DE Whitfield-Gabrieli, Susan |
| author_sort | Bauer, Clemens CC |
| collection | MIT |
| description | © 2020 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. Mindfulness training can enhance cognitive control, but the neural mechanisms underlying such enhancement in children are unknown. Here, we conducted a randomized controlled trial (RCT) with sixth graders (mean age 11.76 years) to examine the impact of 8 weeks of school-based mindfulness training, relative to coding training as an active control, on sustained attention and associated resting-state functional brain connectivity. At baseline, better performance on a sustained-attention task correlated with greater anticorrelation between the default mode network (DMN) and right dorsolateral prefrontal cortex (DLPFC), a key node of the central executive network. Following the interventions, children in the mindfulness group preserved their sustained-attention performance (i.e., fewer lapses of attention) and preserved DMN–DLPFC anticorrelation compared to children in the active control group, who exhibited declines in both sustained attention and DMN–DLPFC anticorrelation. Further, change in sustained-attention performance correlated with change in DMN–DLPFC anticorrelation only within the mindfulness group. These findings provide the first causal link between mindfulness training and both sustained attention and associated neural plasticity. Administered as a part of sixth graders' school schedule, this RCT supports the beneficial effects of school-based mindfulness training on cognitive control. |
| first_indexed | 2024-09-23T12:37:23Z |
| format | Article |
| id | mit-1721.1/134562 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T12:37:23Z |
| publishDate | 2021 |
| publisher | Wiley |
| record_format | dspace |
| spelling | mit-1721.1/1345622023-09-11T20:33:30Z Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial Bauer, Clemens CC Rozenkrantz, Liron Caballero, Camila Nieto-Castanon, Alfonso Scherer, Ethan West, Martin R Mrazek, Michael Phillips, Dawa T Gabrieli, John DE Whitfield-Gabrieli, Susan Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT © 2020 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. Mindfulness training can enhance cognitive control, but the neural mechanisms underlying such enhancement in children are unknown. Here, we conducted a randomized controlled trial (RCT) with sixth graders (mean age 11.76 years) to examine the impact of 8 weeks of school-based mindfulness training, relative to coding training as an active control, on sustained attention and associated resting-state functional brain connectivity. At baseline, better performance on a sustained-attention task correlated with greater anticorrelation between the default mode network (DMN) and right dorsolateral prefrontal cortex (DLPFC), a key node of the central executive network. Following the interventions, children in the mindfulness group preserved their sustained-attention performance (i.e., fewer lapses of attention) and preserved DMN–DLPFC anticorrelation compared to children in the active control group, who exhibited declines in both sustained attention and DMN–DLPFC anticorrelation. Further, change in sustained-attention performance correlated with change in DMN–DLPFC anticorrelation only within the mindfulness group. These findings provide the first causal link between mindfulness training and both sustained attention and associated neural plasticity. Administered as a part of sixth graders' school schedule, this RCT supports the beneficial effects of school-based mindfulness training on cognitive control. 2021-10-27T20:05:35Z 2021-10-27T20:05:35Z 2020 2021-03-22T17:23:14Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/134562 en 10.1002/HBM.25197 Human Brain Mapping Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Wiley Wiley |
| spellingShingle | Bauer, Clemens CC Rozenkrantz, Liron Caballero, Camila Nieto-Castanon, Alfonso Scherer, Ethan West, Martin R Mrazek, Michael Phillips, Dawa T Gabrieli, John DE Whitfield-Gabrieli, Susan Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title | Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title_full | Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title_fullStr | Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title_full_unstemmed | Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title_short | Mindfulness training preserves sustained attention and resting state anticorrelation between default‐mode network and dorsolateral prefrontal cortex: A randomized controlled trial |
| title_sort | mindfulness training preserves sustained attention and resting state anticorrelation between default mode network and dorsolateral prefrontal cortex a randomized controlled trial |
| url | https://hdl.handle.net/1721.1/134562 |
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