Peptide design by optimization on a data-parameterized protein interaction landscape

© 2018 National Academy of Sciences. All rights reserved. Many applications in protein engineering require optimizing multiple protein properties simultaneously, such as binding one target but not others or binding a target while maintaining stability. Such multistate design problems require navigat...

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Bibliographic Details
Main Authors: Jenson, Justin Michael, Xue, Vincent, Stretz, Lindsey, Mandal, Tirtha, Reich, Lothar, Keating, Amy E.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2022
Online Access:https://hdl.handle.net/1721.1/134759.2