Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

© 2017, American College of Rheumatology Objective: Immune dysfunction is an important component of the disease process underlying systemic sclerosis (SSc), but the mechanisms contributing to altered immune cell function in SSc remain poorly defined. This study was undertaken to measure the expressi...

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Bibliographic Details
Main Authors: Fleury, Michelle, Belkina, Anna C, Proctor, Elizabeth A, Zammitti, Christopher, Simms, Robert W, Lauffenburger, Douglas A, Snyder-Cappione, Jennifer E, Lafyatis, Robert, Dooms, Hans
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Wiley 2022
Online Access:https://hdl.handle.net/1721.1/134856.2