Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

© 2018 The Author(s). Scalable, integrative methods to understand mechanisms that link genetic variants with phenotypes are needed. Here we derive a mathematical expression to compute PrediXcan (a gene mapping approach) results using summary data (S-PrediXcan) and show its accuracy and general robus...

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Bibliographic Details
Format:	Article
Language:	English
Published:	Springer Science and Business Media LLC 2021
Online Access:	https://hdl.handle.net/1721.1/135026

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