Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations

Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations

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Inefficient injection of microparticles through conventional hypodermic needles can impose serious challenges on clinical translation of biopharmaceutical drugs and microparticle-based drug formulations. This study aims to determine the important factors affecting microparticle injectability and est...

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Bibliographic Details
Main Authors: Sarmadi, Morteza, Behrens, Adam M, McHugh, Kevin J, Contreras, Hannah TM, Tochka, Zachary L, Lu, Xueguang, Langer, Robert, Jaklenec, Ana
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/135398

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